Relapsing MS Signs and Symptoms

Relapsing MS Signs and Symptoms

Understanding relapses, symptoms, disability progression, and lesions

As your disease progresses, existing symptoms may worsen, or new symptoms may appear during a flare-up. If you have any questions about relapsing MS symptoms, the best source of information is your healthcare provider.

AVONEX is indicated for the treatment of patients with relapsing forms of MS. AVONEX is not indicated to treat the individual symptoms of relapsing MS, including those listed below.

Some of the common symptoms* of relapsing MS include:

  • Bladder and bowel problems
  • Difficulties with attention, learning, and memory
  • Mood changes
  • Fatigue
  • Muscle rigidity or stiffness
  • Weakness or poor coordination
  • Numbness and tingling
  • Pain in arms and legs
  • Visual disturbances

To learn more about the symptoms of relapsing MS, talk with your healthcare provider.

Relapses

Relapses, also known as flare-ups or exacerbations, are new symptoms or a worsening of existing symptoms. Their severity and duration are often unpredictable. If you think that you might be having a relapse, be sure to talk with your healthcare provider.

Flare-ups may vary in severity and can last from a few days to several months. Even infrequent or mild flare-ups can cause permanent damage to the central nervous system and may lead to future disability.

*Currently, there are no disease-modifying therapies (DMTs) indicated to treat the symptoms listed, including AVONEX.

MS causes brain lesions that can be detected by MRI

MS causes brain lesions that can be visualized with magnetic resonance imaging (MRI). MRIs are able to show both recent lesion development and previous lesion damage. Some common types of lesions that can be visualized with MRIs include:

  • Gd+ enhanced lesions: Lesions that show active inflammation using a dye containing gadolinium
  • T2 lesions: Lesions that show the long-term impact of inflammation on the brain
  • T1 lesions: Lesions that show damage that may be permanent

The exact relationship between MRI findings and your overall health is not clear. However, MRIs are commonly used to help you and your healthcare provider track MS activity in your body.

Healthcare providers can’t say for sure if there is a link between brain lesions and the progression of physical disability. But, it's important to talk with your neurologist about each one of your MRIs because that may help with working out a treatment plan moving forward.

AVONEX Helpful Tips

Get the guidance you need on taking AVONEX and how it can help you with your relapsing MS.

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Kelly's Story

See Kelly's story and understand why she and her healthcare provider chose to treat her relapsing MS with AVONEX.

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Following Up

Use this guide to help follow up with your healthcare provider after beginning treatment.

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Important Safety Information and Indication

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.

Important Safety Information

Before beginning treatment, you should discuss with your healthcare provider the potential benefits and risks associated with AVONEX.

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

AVONEX will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS. MS is a life-long disease that affects your nervous system by destroying the protective covering (myelin) that surrounds your nerve fibers.

The way AVONEX works in MS is not known. It is not known if AVONEX is safe and effective in children.

Do not take AVONEX if you are allergic to interferon beta, albumin (human), or any of the ingredients in AVONEX.

Before taking AVONEX, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

AVONEX can cause serious side effects including:

Tell your healthcare provider right away if you have any of the symptoms listed above.

The most common side effects of AVONEX include:

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information and Medication Guide for additional important safety information. This information is not intended to replace discussions with your healthcare provider.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.