Once-a-Week AVONEX
AVONEX is the only treatment for relapsing MS offering once-a-week dosing. Now you can focus on you—instead of on your next injection.
And now, with the introduction of AVONEX PEN, a single-use prefilled autoinjector, getting the benefits of once-a-week AVONEX just got easier.a In a study of people already taking AVONEX, 9 out of 10 preferred AVONEX PEN over the prefilled syringe.b,c
In this study, 89% of people correctly followed the instructions for using AVONEX PEN. In fact, there were no device failures and 99% of people got their full dose of AVONEX.
Our shortest needle ever
AVONEX PEN uses a needle that's half the length of the standard needle for the AVONEX Prefilled Syringe. Compare needle sizes
Plus, a built-in shield covers the needle until your injection is over.
It's reassuring to know that in the AVONEX PEN study, people felt significantly less injection pain after they switched from prefilled syringe to AVONEX PEN.d In fact, on a scale from 0 to 10, people rated their level of injection pain with AVONEX PEN at 0.7, compared with 1.7 for AVONEX prefilled syringe.
And, if you experience injection anxiety, you should know that people participating in the study had less injection anxietye and felt more confident self-injectingf with AVONEX PEN than with the AVONEX Prefilled Syringe.
Works all week to fight MS
No matter how you take AVONEX, it's different from all other injectable MS medications. Other injectable MS medications are given under the skin (subcutaneously).
Since AVONEX is given into your muscle tissue (intramuscularly), each injection goes deeper into your tissue, which results in a slow release of medication. That way, AVONEX keeps fighting your relapsing MS all week long—so you don't have to think about your injections again for the rest of the week!
Injection help when you need it
If giving yourself an injection seems scary, know that many people with relapsing MS adjust to the process over time and with proper training. If your doctor prescribes AVONEX to treat your MS, an ActiveNurse™ can give you the in-home training you need—whether you're using AVONEX PEN or an AVONEX syringe.
In addition, an ActiveNurse can train a care partner to help give you your once-a-week AVONEX. Either way, you can contact an ActiveNurse at any time for more advice after you've had your injection training. You can even request additional training sessions—whatever it takes to help you get used to your injections.
So whether you're newly diagnosed, or already on another MS therapy, there's never been a better time to ask your doctor if once-a-week AVONEX is right for you.
- On their last day of the study, people rated ease of injection and ease of holding/gripping AVONEX PEN compared with the prefilled syringe.
- A study to see if people who had used AVONEX prefilled syringe for at least three months were able to successfully use AVONEX PEN. People took AVONEX using the prefilled syringe the first week and then switched to AVONEX PEN for the next three weeks. Results were based on patient and physician questionnaires.
- People were asked to complete a multiple choice questionnaire on their last day of the study, rating their overall experience with AVONEX PEN compared with the prefilled syringe.
- Based on a comparison of injection pain ratings for the prefilled syringe and the third AVONEX PEN injection.
- On their last day of the study, people rated their level of injection anxiety with AVONEX PEN compared with the prefilled syringe.
- On their last day of the study, people rated their confidence self-injecting AVONEX PEN compared with the prefilled syringe.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Please see the full Prescribing Information and Medication Guide for additional important safety information. This information is not intended to replace discussions with your healthcare provider.






