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Help Manage Flu-like Symptoms

People commonly experience flu-like symptoms (FLS) when they first start taking AVONEX. However, many people find that their FLS get milder or go away completely over time, as their bodies adjust to AVONEX. FLS are reactions to your AVONEX injections that may include fever, chills, muscle aches, tiredness, or headache. Experiencing FLS doesn't mean you actually have the flu. These symptoms are part of your body's natural response to interferon beta.

Gradually working your way up to the full dose of AVONEX, a process known as titration, was proven in a clinical study of healthy volunteers to lower the chances of getting FLS and make them less severe. Talk with your doctor to learn more about titrating AVONEX.

If you experience FLS, you may find that they get better over your first few months of treatment. There are also steps you can take that may help to manage them in the meantime:

  • Stay well hydrated.
  • Ask your doctor about over-the-counter pain relievers you can try before and after taking your AVONEX. He or she may suggest taking a PM pain reliever before bed to help you sleep.
  • FLS may peak during different times for each individual. You may want to experiment with different times of the day for your injection. You may find that taking your AVONEX in the morning or afternoon is best.
  • Keep a journal to note how long after your injection any side effects occur, how much water you drink, and any pain relievers you take.

Call an ActiveNurse™ at 1-800-456-2255 for more tips that may help you manage FLS.

In a 2-year study, only 4% (7 out of 158) of patients discontinued AVONEX due to adverse events. Please see below for additional important safety information.

Norma J
Indication

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Please see the full Prescribing Information and Medication Guide for additional important safety information. This information is not intended to replace discussions with your healthcare provider.

 

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