Taking AVONEX® (interferon beta-1a)

Taking AVONEX

One injection a week

With relapsing multiple sclerosis (MS), people often wonder what their dosing schedule will look like once they begin treatment. AVONEX® (interferon beta-1a) is a once-weekly treatment. That means you have only one injection a week.

You can take AVONEX in 3 ways:

avonex-pen

AVONEX PEN

AVONEX PEN is a prefilled, single-use autoinjector that lets you treat your relapsing MS in a single click. It includes a covered needle that's half the length of the standard needle for AVONEX prefilled syringe.

According to a survey of people taking AVONEX who participated in a clinical study (n=74),

9/10preferred this option to AVONEX prefilled syringe.*

Download Injection Guide

avonex-prefilled-syringe

AVONEX
Prefilled Syringe

AVONEX prefilled syringe lets you inject your weekly dose of AVONEX manually.

Talk to your doctor about whether it's right for you.

Download Injection Guide

avonex-powder-form

AVONEX
Powder Form

AVONEX powder form is an unmixed form of AVONEX that was made for use with a standard AVONEX syringe.

Talk with your doctor for further guidance.

Download Injection Guide

The injection process and recommended injection sites are different for each of these options. Make sure that you read the Injection Guide and Instructions for Use for whichever form you and your doctor choose.

Before your first AVONEX injection, set up a training session with your doctor. You can also get additional training from a Nurse Educator to help you inject correctly each time. Because AVONEX is given into the muscle (intramuscularly), it uses a different injection technique than other injectable relapsing MS medications, which are given under the skin (subcutaneously).

So proper training is essential, even if you're already accustomed to giving yourself injections.

titrating-syringe

Titrating AVONEX

During the start of your treatment, your doctor may recommend you build up to a full dose of AVONEX gradually over the first month. This is a process called "titration."

In a clinical study of healthy volunteers, people who titrated AVONEX experienced fewer and milder flu-like symptoms.

The AVOSTARTGRIP® Titration Kit, which is used with the AVONEX prefilled syringe, can help you get started with titration. You should download and review the Instructions for Use before your training session.

Download Instructions

*

According to a survey of people taking AVONEX who participated in a clinical study (n=74), 9 out of 10 preferred AVONEX PEN to the AVONEX prefilled syringe. People took AVONEX using the prefilled syringe the first week and then switched to AVONEX PEN for the next 3 weeks. Results were based on patient and physician questionnaires.

On their last day of the survey, people rated AVONEX PEN better than the prefilled syringe on ease of injection and ease of holding/gripping.

People were asked to complete a questionnaire on their last day of the survey, rating their overall experience with AVONEX PEN compared with the AVONEX prefilled syringe.

On their last day of the survey, people rated their ability to self-inject AVONEX PEN compared with AVONEX prefilled syringe.

Based on a comparison of injection pain ratings for AVONEX prefilled syringe and the third AVONEX PEN injection.


Starting AVONEX
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Important Safety Information and Indication

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.

Important Safety Information

Before beginning treatment, you should discuss with your healthcare provider the potential benefits and risks associated with AVONEX.

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

AVONEX will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS. MS is a life-long disease that affects your nervous system by destroying the protective covering (myelin) that surrounds your nerve fibers.

The way AVONEX works in MS is not known. It is not known if AVONEX is safe and effective in children.

Do not take AVONEX if you are allergic to interferon beta, albumin (human), or any of the ingredients in AVONEX.

Before taking AVONEX, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

AVONEX can cause serious side effects including:

Tell your healthcare provider right away if you have any of the symptoms listed above.

The most common side effects of AVONEX include:

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information and Medication Guide for additional important safety information. This information is not intended to replace discussions with your healthcare provider.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.