Taking AVONEX® (interferon beta-1a)

Taking AVONEX

Getting started on treatment

Getting started on treatment is one of the most important decisions you can make. Treatment with AVONEX has been proven to help delay physical disability progression and reduce flare-ups.

Talk with your care partner to find out if AVONEX is right for you, then get started in 3 simple steps:

  • Step 1: Get your prescription
  • If you and your healthcare provider decide that AVONEX is right for you, and we receive your START Form, you're on your way. The AVONEX START Form can help you get started and receive the support you need through MS ActiveSource®.

    Learn more about AVONEX START

  • Step 2: Get insurance assistance
  • We are here to help you focus on your treatment, not its cost. ActiveAccess™ offers a comprehensive set of financial and insurance support services with solutions tailored to your individual needs. To see how we can help, call 1-800-456-2255.

    Learn more about ActiveAccess™

  • Step 3: Get injection training
  • The ActiveNurse™ Educators program provides FREE in-home training from a licensed, MS-trained nurse. ActiveNurse™ Educators will teach you and/or your care partners the skills needed to give an injection properly. They're available 24/7. So when you're ready to schedule your first training session, or if you have any additional questions, call 1-800-456-2255.

    Learn more about ActiveNurse™ Educators

AVONEX can cause serious side effects including heart problems, blood problems, seizures, infections, and thyroid problems including problems concentrating, feeling cold or hot all the time, weight changes, and skin changes. Tell your healthcare provider right away if you experience any of these symptoms while taking AVONEX.

Once-a-week dosing schedule

AVONEX is a once-a-week treatment for relapsing MS. Remember, you can only get the benefits of a treatment that you're taking as prescribed. Think about whether a once-a-week treatment might fit your schedule.

3 dosing options

AVONEX is available in 3 different forms, allowing you and your healthcare provider to choose the one that works best for you.

  • AVONEX PEN
  • A single-use, prefilled autoinjector that uses a covered needle that's 50% shorter than the standard needle for AVONEX Prefilled Syringe. With AVONEX PEN, you take AVONEX with one click, just once a week. According to a survey of people taking AVONEX who participated in a clinical study (n=74), 9 out of 10 preferred this option to AVONEX Prefilled Syringe.

    Download AVONEX PEN Injection Guide

  • AVONEX in Powdered Form
  • AVONEX in Powdered Form is an unmixed form of AVONEX that was made for use with a standard AVONEX syringe. Talk with your healthcare provider for further guidance.

    Download in Powdered Form Injection Guide

The injection process and recommended injection sites are different for each of these forms. Make sure that you read the injection guide and instructions for use for whichever form you and your healthcare provider choose. You can download each injection guide here:

Download AVONEX PEN

Download AVONEX Prefilled Syringe Injection Guide

Download AVONEX in Powdered Form Injection Guide

Most people who take AVONEX have flu-like symptoms early during the course of therapy. Usually, these symptoms last for a day after the injection. You may be able to manage these flu-like symptoms by taking over-the-counter pain and fever reducers. For many people, these symptoms lessen or go away over time. Symptoms may include muscle aches, fever, tiredness, and chills.

Before your first AVONEX injection, set up a training session with your healthcare provider. You can also get training from an AVONEX ActiveNurse™ Educator to help you inject correctly each time. Because AVONEX is given into the muscle (intramuscularly), it uses a different injection technique than other injectable relapsing MS medications, which are given under the skin (subcutaneously). So proper training is essential, even if you're already accustomed to giving yourself injections.

The AVOSTARTGRIP® Titration Kit

During the start of your treatment, to help reduce flu-like symptoms, your healthcare provider may recommend you build up to a full dose of AVONEX gradually over the first month. This is a process called "titration." After your first month, you can continue using either AVONEX Prefilled Syringe or begin using AVONEX PEN depending on your healthcare provider's recommendation.

In a clinical study of healthy volunteers, people who titrated AVONEX experienced fewer and milder flu-like symptoms.

The AVOSTARTGRIP® Titration Kit uses AVONEX Prefilled Syringe, but after you've completed the initial 4 titration doses, you can easily move on to AVONEX PEN.

Review the Instructions for Use below before your training session with an AVONEX ActiveNurse™ Educator. The Instructions will show you how to:

  • Prepare for your weekly injection
  • Use the AVOSTARTGRIP® devices
  • Take your injection
  • Dispose of used syringes, needles, and titration devices

Download AVOSTARTGRIP® Titration Kit

Staying on AVONEX

With the guidance of your healthcare provider, and the support of family and friends, you have started the process of treating your relapsing MS. And with AVONEX, the once-a-week dosing schedule allows you to make injections a part of your routine.


Learn about the AVONEX safety and side effect profile and work with your healthcare provider to find ways to help.
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Important Safety Information and Indication

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.

Important Safety Information

Before beginning treatment, you should discuss with your healthcare provider the potential benefits and risks associated with AVONEX.

AVONEX can cause serious side effects. Tell your healthcare provider right away if you have any of the symptoms listed below while taking AVONEX.

AVONEX will not cure your MS but may decrease the number of flare-ups of the disease and slow the occurrence of some of the physical disability that is common in people with MS. MS is a life-long disease that affects your nervous system by destroying the protective covering (myelin) that surrounds your nerve fibers.

The way AVONEX works in MS is not known. It is not known if AVONEX is safe and effective in children.

Do not take AVONEX if you are allergic to interferon beta, albumin (human), or any of the ingredients in AVONEX.

Before taking AVONEX, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

AVONEX can cause serious side effects including:

Tell your healthcare provider right away if you have any of the symptoms listed above.

The most common side effects of AVONEX include:

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information and Medication Guide for additional important safety information. This information is not intended to replace discussions with your healthcare provider.

Indication

AVONEX (interferon beta-1a) is approved by FDA to treat relapsing forms of multiple sclerosis (MS) to decrease the number of flare-ups and slow the occurrence of some of the physical disability that is common in people with MS. AVONEX is approved for use in people who have experienced a first attack and have lesions consistent with MS on their MRI.